In traditional Alzheimer’s research and treatment, the field is shifting from symptom management toward disease-modifying therapies, yet the structure for monitoring has not evolved. This presents a clinical and economically consequential gap: most patient assessments occur in structured clinical settings and do not measure how individuals function between visits.
Grasshopper Health is a catalyst for change with the Axis PatchTM. By integrating with a patient’s smartphone, we enable continuous and non-intrusive gait analysis throughout everyday activities.
By introducing daily monitoring into Alzheimer’s research and care, Grasshopper supports safety surveillance, trial enrichment and early disease insights.
Alzheimer’s disease is a progressive and irreversible brain disorder that damages nerve cells. It’s the most common cause of dementia in older adults.
In 2025, over 7.2 million Americans aged 65 and older lived with Alzheimer’s, and it remains the 6th leading cause of death.
The 2025 Alzheimer’s Disease Facts and Figures noted that 80% of Americans would want to know if they had Alzheimer’s disease before having symptoms or before interfered with their daily life.
With Alzheimer’s, affected individuals often exhibit distinct gait changes, including:
These mixed patterns can develop gradually and fluctuate day-to-day, making them easy to miss without continuous, real-world monitoring. The Axis PatchTM captures these shifts over time, providing researchers and clinicians with clearer insight into functional change.
The Axis Patch™ supports clinicians by providing: